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Analysis of Counterfeit Medicines from the Perspective of Medicines Policy
Boltnarová, Barbora ; Kostřiba, Jan (advisor) ; Zubrová, Julie (referee)
Charles University, Faculty of Pharmacy in Hradec Kralove Department of Social and Clinical Pharmacy Author Barbora Boltnarová Supervisor PharmDr. Jan Kostriba, Ph.D. Title of Diploma Thesis Analysis of Counterfeit Medicines from the Perspective of Medicines Policy Objectives: The aim of the theoretical part of this diploma thesis was the analysis of the counterfeiting of medicinal products and a summary of the most critical topics and issues related to this illegal activity. Another purpose of the theoretical part was the mapping of trends in counterfeiting of medicinal products on the domestic and world scale and to compile a summary of the instruments used to combat counterfeiting of medicinal products. The aim of the practical part was the analysis of the reports of falsified medicinal products and to compare the obtained results with hypotheses based on theoretical knowledge. Methods: The data was obtained by analyzing the reports of counterfeit medicinal products published by State Institute for Drug Control in the period from 2nd March 2006 to 14th November 2017. Altogether, 115 reports from the Czech Republic and from abroad were analyzed. Results: The results of the analysis show that the situation regarding counterfeiting of medicinal products in the Czech Republic is relatively safe...
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Parameters of Drug Assessment in the Therapy of Rare Diseases
Ornstová, Eva ; Kostřiba, Jan (advisor) ; Klimeš, Jiří (referee)
Charles University in Prague, Faculty of Pharmacy in Hradec Králové Department of Social and Clinical Pharmacy Candidate Mgr. Eva Ornstová Consultant PharmDr. Jan Kostřiba, Ph.D Title of Thesis PARAMETERS OF DRUG ASSESSMENT IN THE THERAPY OF RARE DISEASES KEY WORDS: rare diseases, health technology assessment, health policy, drug policy OBJECTIVES The aim of this study was to find out how can the use of multiple criteria in Health technology assessment (HTA) influence outcome in different drug categories. Especially in relationship to orphan medicinal products. Next objective was to explore, which criteria are the most important in the value of the drug and to measure the difference in the preferences among three stakeholder groups in the Czech Republic. METHODS The set of 10 criteria was selected by the expert panel and 3 model treatments were described. Two-round questionnaire was developed and distributed among highly qualified representatives of three stakeholder groups (patients or carers, clinicians and policy makers). In the first round participants provided weights for each criterion by answering on the scale from 1 to 7. In second round participants scored model treatments according to their performance in each criterion. Normalized weights were combined with scores and treatments were...
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Analysis of Marketing Strategies of Pharmacies
Mikulcová, Jitka ; Kostřiba, Jan (advisor) ; Pokladníková, Jitka (referee)
The theoretical part of this diploma thesis defines basic terms related to the marketing and gives a general overview of marketing strategies. It also evaluates the importance of marketing in public health services and describes possibilities of internet health technologies that patients use for the contact with health professionals and getting information about health. The practical part analyzes patients' opinion on pharmacy marketing practice and importance of internet communication. Data were collected via the questionnaire survey among the users of internet and Facebook and customers in one independent community pharmacy in Beroun. Practical part also refers about the experimental marketing campaign that was performed in the pharmacy in Beroun and that focused on the creating promotion materials and technologies of internet communication. According to results, many patients appreciate marketing activities of community pharmacies. There is also noticeable a positive trend of using the web sites and social media to connect with the community pharmacy. Key words: marketing, healthcare, community pharmacy, internet, social media, the Czech Republic
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Analysis of Counterfeit Medicines from the Perspective of Medicines Policy
Boltnarová, Barbora ; Kostřiba, Jan (advisor) ; Zubrová, Julie (referee)
Charles University, Faculty of Pharmacy in Hradec Kralove Department of Social and Clinical Pharmacy Author Barbora Boltnarová Supervisor PharmDr. Jan Kostriba, Ph.D. Title of Diploma Thesis Analysis of Counterfeit Medicines from the Perspective of Medicines Policy Objectives: The aim of the theoretical part of this diploma thesis was the analysis of the counterfeiting of medicinal products and a summary of the most critical topics and issues related to this illegal activity. Another purpose of the theoretical part was the mapping of trends in counterfeiting of medicinal products on the domestic and world scale and to compile a summary of the instruments used to combat counterfeiting of medicinal products. The aim of the practical part was the analysis of the reports of falsified medicinal products and to compare the obtained results with hypotheses based on theoretical knowledge. Methods: The data was obtained by analyzing the reports of counterfeit medicinal products published by State Institute for Drug Control in the period from 2nd March 2006 to 14th November 2017. Altogether, 115 reports from the Czech Republic and from abroad were analyzed. Results: The results of the analysis show that the situation regarding counterfeiting of medicinal products in the Czech Republic is relatively safe...
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Analysis of Marketing Strategies of Pharmacies
Mikulcová, Jitka ; Kostřiba, Jan (advisor) ; Pokladníková, Jitka (referee)
The theoretical part of this diploma thesis defines basic terms related to the marketing and gives a general overview of marketing strategies. It also evaluates the importance of marketing in public health services and describes possibilities of internet health technologies that patients use for the contact with health professionals and getting information about health. The practical part analyzes patients' opinion on pharmacy marketing practice and importance of internet communication. Data were collected via the questionnaire survey among the users of internet and Facebook and customers in one independent community pharmacy in Beroun. Practical part also refers about the experimental marketing campaign that was performed in the pharmacy in Beroun and that focused on the creating promotion materials and technologies of internet communication. According to results, many patients appreciate marketing activities of community pharmacies. There is also noticeable a positive trend of using the web sites and social media to connect with the community pharmacy. Key words: marketing, healthcare, community pharmacy, internet, social media, the Czech Republic
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The Pharmaceutical Lobby in the Czech Republic
Škrobáková, Irena ; Vymětal, Petr (advisor) ; Matějková, Adéla (referee)
The pharmaceutical companies are considered as one of the most influential interest groups within drug policy, or in general within healthcare system. Therefore, this diploma thesis is focused on the influence of the pharmaceutical manufacturers on legislative framework that forms the drug policy, on the impact on the concrete implementation of drug policy and finally on the influence on prescription, sales and public opinion. Based on an analysis of the pharmaceutical market and the drug policy of the Czech Republic, the diploma thesis defines the most common interests of the pharmaceutical companies which they are trying to push through lobbying. Furthermore, the thesis identifies the access points through which these interests can push through and tries to illustrate these facts on concrete examples.
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Identifikace a kvalifikovaný odhad nákladů na léčbu cévní mozkové příhody v ČR na základě farmakoekonomické analýzy a návrh alternativního řešení
Pokorná, Hana
Background: Stroke is the second most frequent cause of death in developed countries and the most frequent cause of permanent disability. This way this illness creates high costs for society which should be minimized as much as possible. One of the possibilities is to administer cost-saving drugs which are at the same time from the medical point of view of the top quality and their economic effectiveness can be identified by means of pharmacoeconomic analysis. Objective: The objective of the work is to identify and carry out a quantified estimate of costs connected with the stroke treatment in the Czech Republic. Next is the necessary to confront the results with the alternative solution to the treatment (taking drug Xarelto instead of Warfarin) and to carry out comparison of the both the possibilities from the quantitative point of view. Methods: Costs of stroke treatment are evaluated from the social point of view. From their determination COI method with type of bottom-up approach has been picked out which includes all-life cost-of-illness. For comparison of costs both the treatment vari-ants the Cost-Minimization Analysis (CMA) has been chosen, the results of which shows net cost savings. Data are taken from non-public data of the provider (St. Anne 's Uni-versity Hospital Brno), Institute of Health Information and Statistics of the Czech Republic, Czech Statistical Office, foreign studies and consultations with neurologists as well. Results: Total social costs of treatment of stroke were 12 991 273 843,65 CZK. COI method was used to calculate average costs for one patient with Warfarin in the amount of 1 203 423,68 CZK, in case of alternative treatment with Xarelto in the amount of 1 465 963,32 CZK. Relaps creates the biggest item of the costs. CMA method was used to identify savings when Warfarin is administered in the average amount of 262 539,64 CZK per patient. The hypothesis that Xarelto is more effective from the economic point of view has not been confirmed. Conclusion: Because of high cost of Xarelto, this drug has not beaten the economic effectiveness of Warfarin with lower quality. It is possible to search for savings in other items of identified costs as well.
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Comparison of Czech and French Drug Policies
Jelínková, Věra ; Maaytová, Alena (advisor) ; Blažek, Petr (referee)
The main aim of the thesis is to compare the drug policies of the Czech Republic and France from the point of achieving their partial objectives. The first chapter characterizes the Czech drug policy, the second concentrates on the French drug policy. The third chapter compares both systems on the basis of health statistics, then according to the public expenditure on drugs and it particularly compares the measures of the drug policies which are used to reach their specific objectives. At the end there is a selection of some of the French measures which could be implemented in the Czech drug policy.
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